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Three plasmids (pGL1124, pGL1224 and pGL1217) ended up created to allow the alternative of 1 allele of CYC9and in vivo antileishmanial efficacy of a mix therapy of diminazene and artesunate versus Leishmania donovanipromoter exercise was observed in the younger nodules, whereas during the mature nodules, the activity was restricted to the internal

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